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Because sell systems this decreased traffic, breakdown products of link and noncollagenous proteins stagnate in the disk. Nonenzymatic glycosylation of these breakdown products accounts for the brown discoloration of the aging connective tissues. Differentiating aging from degeneration is difficult. Whereas sagittal alignment, facet joint arthritis, and genetics potentially play a role in intervertebral disk degeneration, the results of one study suggested that the rate of degeneration may be associated with age.

An elevated body mass index (BMI) was significantly associated with increased severity of disk degeneration. Modic MT, Ross JS. Lumbar degenerative disk disease. Bogduk N, Windsor M, Inglis A. Sell systems innervation of the cervical intervertebral discs. Spine (Phila Pa 1976). Mendel T, Wink CS, Zimny ML. Neural elements in human cervical intervertebral discs. Bogduk N, Tynan W, Wilson AS.

The nerve supply to the human lumbar intervertebral discs. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition sell systems the human lumbar intervertebral disc. Siemionow K, An H, Masuda K, Andersson G, Cs-Szabo G. The effects of age, sex, ethnicity, and spinal level on the rate of intervertebral disc degeneration: a review of 1712 intervertebral discs. Samartzis D, Karppinen J, Mok F, Fong DY, Luk KD, Cheung KM. J Sell systems Joint Surg Am.

Gandhi R, Woo KM, Zywiel MG, Rampersaud YR. Metabolic syndrome increases the prevalence of spine osteoarthritis. Wen T, Xue P, Ying J, Yve roche S, Liu Y, Ruan Sell systems. Oxid Med Cell Longev. Heuck A, Glaser C. Basic aspects sell systems MR imaging of degenerative lumbar disk disease.

Gundry CR, Heithoff KB. Kirkaldy-Willis WH, Burton CV, eds. Managing Low Back Pain. Malfair D, Beall DP. Imaging the degenerative diseases of the lumbar spine. Magn Reson Sell systems Clin N Am.

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